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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCN6
All Species:
27.58
Human Site:
Y681
Identified Species:
46.67
UniProt:
P51797
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51797
NP_001277.1
869
97217
Y681
R
S
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Chimpanzee
Pan troglodytes
XP_514393
802
89426
C623
S
S
E
L
R
N
M
C
D
E
H
I
A
S
E
Rhesus Macaque
Macaca mulatta
XP_001104721
869
97094
Y681
R
S
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Dog
Lupus familis
XP_535404
889
99260
Y701
R
S
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Cat
Felis silvestris
Mouse
Mus musculus
O35454
870
96962
Y682
R
G
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Rat
Rattus norvegicus
P51799
803
88712
T624
P
V
T
S
H
S
L
T
A
R
E
V
M
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516296
878
97865
Y690
R
S
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Chicken
Gallus gallus
XP_417644
868
97172
Y680
R
S
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Frog
Xenopus laevis
Q9W701
689
76782
A510
V
I
L
C
V
L
I
A
N
A
F
T
Q
K
L
Zebra Danio
Brachydanio rerio
XP_696527
863
96883
Y675
R
C
Q
S
M
K
S
Y
P
S
S
E
L
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396520
803
89642
S624
I
Y
A
S
E
I
M
S
H
P
I
V
T
L
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193438
761
83935
R582
S
A
D
A
V
T
S
R
N
M
M
F
K
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92943
792
87043
G613
A
D
V
A
S
I
L
G
S
N
K
H
N
G
F
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
E600
S
K
L
I
T
I
N
E
T
I
Y
L
S
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
99.4
93.3
N.A.
96.7
40.8
N.A.
81.3
93.2
22.7
82.6
N.A.
N.A.
37.9
N.A.
49.8
Protein Similarity:
100
92.2
99.8
95.1
N.A.
98.7
58
N.A.
85.3
97.8
39.1
90.7
N.A.
N.A.
57.3
N.A.
64.6
P-Site Identity:
100
6.6
100
100
N.A.
93.3
6.6
N.A.
100
100
0
93.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
93.3
13.3
N.A.
100
100
20
93.3
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
42.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
15
0
0
0
8
8
8
0
0
8
0
8
% A
% Cys:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
8
0
8
8
50
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
8
0
8
8
0
0
0
% H
% Ile:
8
8
0
8
0
22
8
0
0
8
8
8
0
0
0
% I
% Lys:
0
8
0
0
0
50
0
0
0
0
8
0
8
8
8
% K
% Leu:
0
0
15
8
0
8
15
0
0
0
0
8
50
8
15
% L
% Met:
0
0
0
0
50
0
15
0
0
8
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
15
8
0
0
8
8
50
% N
% Pro:
8
0
0
0
0
0
0
0
50
8
0
0
0
0
0
% P
% Gln:
0
0
50
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
50
0
0
0
8
0
0
8
0
8
0
0
0
50
0
% R
% Ser:
22
43
0
65
8
8
58
8
8
50
50
0
8
15
0
% S
% Thr:
0
0
8
0
8
8
0
8
8
0
0
8
8
0
8
% T
% Val:
8
8
8
0
15
0
0
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
50
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _